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Abstract:

Background: mortality in polytrauma with pelvic injuries and intrapelvic bleeding remains high and can be reduced through a multidisciplinary approach to hemostasis.

Aim: was to determine possibilities and tactics of using endovascular interventions to stop intrapelvic bleeding in polytrauma with pelvic injuries.

Material and methods: a search was made for scientific articles in the PubMed database and the Scientific Electronic Library (eLIBRARY.ru), published from 2017 to 2021. Transcatheter embolization of pelvic arteries is an effective method for stopping intrapelvic bleeding and is indicated for detecting extravasation of contrast in computed tomography and angiography. In patients with unstable hemodynamics, embolization can be used if it is possible to perform it no later than 30-60 minutes after the detection of intrapelvic bleeding. Resuscitation endovascular balloon occlusion of the aorta can serve as an important component of the damage control strategy and a bridge to the application of methods for the final control of abdominal and intrapelvic bleeding in patients with unstable hemodynamics and systolic blood pressure less than 70 mm hg.

Conclusion: methods of endovascular surgery do not oppose and do not exclude the use of extraperitoneal pelvic packing and/or external fixation of the pelvis to stop intrapelvic bleeding in case of polytrauma. The choice of methods of hemostasis and the algorithm for their application are determined by the degree of hemodynamic disturbances, the presence of combined injuries, the data of radiation diagnostics, and the technical and logistical resources of the trauma center.

 

Abstract:

Background: coronavirus disease is characterized by hypercoagulation and requires treatment with anticoagulants. At the background of anticoagulant therapy, life-threatening soft tissue bleeding may occur.

Aim: was to evaluate the efficacy of transcatheter arterial embolization in patients with severe COVID-19 complicated by soft tissue bleeding.

Materials and methods: within the period from January 30, 2021 to February 18, 2022, transcatheter arterial embolization of soft tissue bleeding was performed in 25 patients with COVID-19-associated pneumonia.

Results: transcatheter arterial embolization was performed in 19 of 25 patients (76%). Postoperative mortality was 42%, and overall mortality was 40%. Fifteen patients (60%) were discharged in satisfactory condition.

Conclusions: severe soft tissue bleeding may occur in patients with coronavirus disease while treated with anticoagulants. The method of choice for treatment of these hemorrhages is transcatheter arterial embolization.

 

 

Abstract:

Introduction: osteoarthritis (OA) is the most common disease of the musculoskeletal system, the main cause of pain development, loss of joint function and, as a consequence, one of leading factors of population disability. Treatment strategy for patients with gonarthrosis is not fully defined, especially in patients with grade 1-2. In this cohort of patients, conservative treatment is indicated, but it does not always lead to a decrease in the severity of pain, significantly reducing the quality of life. One of treatment options for such patients is transcatheter embolization of the hypervascular area of popliteal arteries.

Aim: was to present a case report of the successful use of transcatheter arterial embolization of branches of the popliteal artery in gonarthrosis.

Materials and methods: patient B., 72 years old, consulted a rheumatologist in November 2019 with complaints on pain in knee joints, aggravated by movements, going up and down stairs, as well as pain in the area of small joints of the feet, ankle, and shoulder joints. In view of the ineffectiveness of conservative therapy, patient was offered transcatheter embolization of branches of the hypervascular area of the popliteal artery. Selective embolization of the artery of the hypervascular vasculature of right knee joint was performed under local anesthesia.

Results: 1 month after the procedure, patient noticed a significant decrease in the intensity of pain in right knee joint, increased range of motion. The result of filling out the WOMAC questionnaire 1 month after embolization of popliteal artery branches was 26 points (satisfactory result). At the visit 3 months after the manipulation, patient noted the persistence of effect of procedure. The result of the WOMAC questionnaire is 22 points.

Conclusions: transcatheter arterial embolization of the hypervascular area in osteoarthritis of various origins and localization can be successfully used as an alternative treatment if conservative therapy is ineffective and if there are contraindications to surgical treatment.

 

 

References

1.     Bannuru RR, et al. OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis and cartilage. 2019; 27(11): 1578-1589.

2.     Spitaels D, et al. Epidemiology of knee osteoarthritis in general practice: a registry-based study. BMJ open. 2020; 10(1).

3.     Litwic A, et al. Epidemiology and burden of osteoarthritis. British medical bulletin. 2013; 105(1): 185-199.

4.     Kabalyk MA. Prevalence of osteoarthritis in Russia: regional aspects of trends in statistical parameters during 2011-2016. Rheumatology Science and Practice. 2018; 56(4): 416.

5.     Vitaloni M, et al. Global management of patients with knee osteoarthritis begins with quality of life assessment: a systematic review. BMC musculoskeletal disorders. 2019; 20(1): 493.

6.     Gr?ssel S, Muschter D. Peripheral nerve fibers and their neurotransmitters in osteoarthritis pathology. International Journal of Molecular Sciences. 2017; 18(5): 931.

7.     Okuno Y, et al. Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis. CardioVascular and Interventional Radiology. 2015; 38(2): 336-343.

8.     Landers S, et al. Protocol for a single-centre, parallel-arm, randomised controlled superiority trial evaluating the effects of transcatheter arterial embolisation of abnormal knee neovasculature on pain, function and quality of life in people with knee osteoarthritis. BMJ open. 2017; 7(5).

9.     Palazzo C, et al. Risk factors and burden of osteoarthritis. Annals of physical and rehabilitation medicine. 2016; 59(3): 134-138.

10.   McAlindon TE, Bannuru RR, Sullivan MC, et al. OARSI guidelines for the non-surgical management of knee osteoarthritis. Osteoarthritis and Cartilage. 2014; 22(3): 363-388.

11.   Dieppe P, Lim K, Lohmander S. Who should have knee joint replacement surgery for osteoarthritis? International Journal of Rheumatic Diseases. 2011; 14(2): 175-80.

12.   Kim JR, Yoo JJ, Kim HA. Therapeutics in osteoarthritis based on an understanding of its molecular pathogenesis. International journal of molecular sciences. 2018; 19(3): 674.

13.   William HR, Christin ML, Qian W, et al. Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nature Reviews Rheumatology. 2016; 12(10): 580-592.

14.   Yiyun W, Jiajia X, Xudong Z, et al. TNF-?-induced LRG1 promotes angiogenesis and mesenchymal stem cell migration in the subchondral bone during osteoarthritis. Cell Death and Disease. 2017; 8(3): 2715-2715.

15.   Turovskaya EF, Alekseeva LI, Filatova EG. Current ideas about the pathogenetic mechanisms of pain in osteoarthrosis. Scientific and practical rheumatology. 2014; 52 (4): 438-444 [In Russ].

16.   Mapp PI, Walsh DA. Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. National Reviews Rheumatalogy. 2012; 8(7): 390.

17.   Ashraf S, Mapp PI, Walsh DA. Contributions of angiogenesis to inflammation, joint damage, and pain in a rat model of osteoarthritis. Arthritis & Rheumatology. 2011; 63(9): 2700-2710.

 

Abstract:

Hemobilia is known as one of the most severe complications of percutaneous transhepatic biliary drainage. In the present case, the severe bleeding developed as a result of balloon dilatation and stenting of malignant stricture. Emergency transhepatic arterial embolization was performed with good results. We also discuss 7 cases of hemobilia in our hospital, 3 of which were successfully treated with transcatheter embolotherapy. We conclude that transhepatic arterial embolization appears to be effective and safe treatment for massive hemobilia.

 

References 

 

1.         Хачатуров А.А., Капранов С.А., Кузнецова В.Ф. и др. Актуальные вопросы чреспече-ночного эндобилиарного стентирования при злокачественных блоках желчеотделения. Диагностическая и интервенционная радиология. 2008; 2 (3): 33-47.

 

 

2.         Борисов А.Е., Борисова Н.А., Непомнящая С.Л. Диагностика и лечение гемобилии. Анн. хир. гепатологии. 2005; 10 (1): 40-45.

 

 

3.         Savader S.J., Trerotola S.O., Merine D.S. et al. Hemobilia after percutaneous transhepatic billiary drainage. Treatment with transcathe-ter embolotherapy. J.Vasc. Intervent. Radiol. 1992; 3 (2): 345-352.

 

 

4.         Winick A.B., Waybill P.N., Venbrux A.C. Complications of percutaneous transhepatic biliary interventions. Tech. Vasc. Intern Radiol. 2001; 4 (3): 200-206.

 

 

5.         Fidelman N., Bloom A.I., Kerlan R.K. et al.Hepatic arterial injuries after percutaneous biliary interventions in the era of laparoscopic surgery and liver transplantation. Experience with 930 patients. Radiology. 2008; 247 (3):880-886.

 

 

6.         Saad W.E., Davies M.G., Darcy M.D. Management of bleeding after percutaneous transhepatic cholangiography or transhepatic biliary drain placement. Tech. Vasc. Interv. Radiol. 2008; 11 (1): 60-71.

 

 

7.         Green M.H., Duell R.M., Johnson C.D, Jamieson N.V. Haemobilia. Br. J. Surg. 2001; 88 (6):773-786.

 

 

8.         Hsu K.L., Ko S.F., Chou F.F. et al. Massive hemo-bilia. Hepatogastroenterology. 2002; 49 (44): 306-310.

 

 

9.         Долгушин Б.И., Виршке Э.Р., Черкасов В.А.и др. Селективная эмболизация печеночных артерий при геморрагических осложнениях    чрескожной    чреспеченочной холангиографии. Анн. хир. гепатологии. 2007; 12 (4): 63-68.

 

 

10.     Eurvilaichit C. Iatrogenic hemobilia. Management with transarterial embolization using gelfoam articles. J. Med. Assoc. Thai. 1999; 82 (9): 931-937.

 

 

11.     Park J.Y., Ryu H., Bang S. et al. Hepatic artery pseudoaneurysm associated with plastic biliary stent. Yonsei. Med. J. 2007; 48 (3): 546-548.

 

 

12.     Hammer F.D., Goffette P.P., Mathurin P. Glue embolization of a ruptured pancreaticoduo-denal artery aneurysm. Case report. Eur. Radiol. 1996; (4): 514-517.

 

 

13.     Merrell S.V., Gibberston J.J., Albo D. et al. Atraumatic hemobilia arising from cirrhotic liver. Surgery. 1989; 106 (1): 105-109.

 

 

14.     Rai R., Rose J., Manas D. Potentially fatal hae-mobilia due to inappropriate use of an expanding biliary stent. World. J. Gastroenterol. 2003; 9 (10): 2377-2378.

 

15.     Dousset B., Sauvanet A., Bardou M. et al. Selective surgical indications for iatro-genic hemobilia. Surgery. 1997; 121 (1): 37-41.

 

 

Abstract:

Some authors point out that transcatheter arterial embolization is an effective method of hemostasis. In medical literature this method of hemostasis is not covered sufficiently.

The period under analysis is 200412008. During this period 13 patients with gastro1duodenal hemorrhage underwent endovascular interventon. Among those patients there were 6 women and 7 men at 43 to 85.

All the patients were initially in bad condition.

In 2 cases the source of bleeding was duodenal ulcer, in 2 cases it was pancreatolysis in the phase of mattery fusion of parapancre1atic infiltrate, in 1 case it was hemorrhage in the postoperative period after the operation, performed in the case of choledocholithiasis, in 3 cases it was hemorrhage from the cancerous growth of the duodenal mamelon, in 3 cases the source of bleeding was putres1 cent cancer of the head of pancreas, in 1 case it was cancer of gall bladder, attaching dodecadactylon, in 1 case it was ventrical vari1cosity accompanied by left portal hypertension, which developed after previous pancreatolysis.

Actions performed: 10 gastro1duodenal artery embolizations, in 2 cases combined with embolization of the common hepatic artery, in 1 case combined with embolization of the lower pancreaticoduodenal artery; in 1 case isolated infusion of haemostatics into the gastroduodenal artery was performed, in 1 case it was embolization of the lower pancreaticoduodenal artery, in 1 case it was truncal embolization of the splenic artery.

All the patients had hemostasis achieved. No recurrent hemostasis was observed during the whole period of the patient care.

 

 

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